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SMG8 [cytosol]
Stable Identifier
R-CFA-927759
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
SMG8, A0A8I3PWU0
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Canis familiaris)
Nonsense-Mediated Decay (NMD) (Canis familiaris)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
SMG8 [cytosol] (Canis familiaris)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
SMG8 [cytosol] (Canis familiaris)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
SMG8 [cytosol] (Canis familiaris)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
SMG8 [cytosol] (Canis familiaris)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Canis familiaris)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
SMG8 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PWU0
Gene Names
SMG8
Reference Genes
BioGPS Gene:491116 SMG8
ENSEMBL:ENSCAFG00845024758.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845024758.1 SMG8
KEGG Gene (Canis lupus familiaris):491116 SMG8
Monarch:491116 SMG8
NCBI Gene:491116 SMG8
Reference Transcript
RefSeq:XM_548236.5 SMG8
Other Identifiers
491116
CfaAffx.26910.1.S1_at
GO:0000184
GO:0016071
Participates
as a component of
SMG1:SMG8:SMG9 Complex [cytosol] (Canis familiaris)
Inferred From
SMG8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_548236.1
OpenTargets
ENSG00000167447
Ensembl
ENSCAFT00845043683
,
ENSCAFG00845024758
,
ENSCAFP00845034226
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