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High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]
Stable Identifier
R-CFA-914021
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GRB2:GAB2 [cytosol]
(Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]
(Canis familiaris)
Participates
as a member of
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
Inferred From
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]
(Homo sapiens)
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