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High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]
Stable Identifier
R-CFA-913422
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
SHP1 and SHP2 bind the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
Participants
members
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane]
(Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane]
(Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane]
(Canis familiaris)
Participates
as an input of
SHP1 and SHP2 bind the common beta chain (Canis familiaris)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Canis familiaris)
as a component of
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
as an output of
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
Inferred From
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]
(Homo sapiens)
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