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IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane]
Stable Identifier
R-CFA-913357
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
SHP1 and SHP2 bind the common beta chain (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IL5 homodimer:IL5RA [plasma membrane]
(Canis familiaris)
pY593,Y628-IL3RB:JAK2 [plasma membrane]
(Canis familiaris)
Participates
as a component of
High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Canis familiaris)
Inferred From
IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane]
(Homo sapiens)
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