Reactome | ATP6V1D [cytosol]

ATP6V1D [cytosol]

Stable Identifier

R-CFA-912597

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

ATP6V1D, E2QVC0

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Canis familiaris)

- Cellular responses to stress (Canis familiaris)
  - Amino acids regulate mTORC1 (Canis familiaris)
    - RRAGA,B exchanges GDP for GTP (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - RRAGA,B hydrolyzes GTP (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - RRAGC,D exchanges GTP for GDP (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - RRAGC,D hydrolyzes GTP (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - mTORC1 binds RHEB:GTP (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
    - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Canis familiaris)
        
        v-ATPase:Ragulator [lysosomal membrane] (Canis familiaris)
        
        v-ATPase [lysosomal membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by Receptor Tyrosine Kinases (Canis familiaris)
  - Signaling by Insulin receptor (Canis familiaris)
    - Insulin receptor recycling (Canis familiaris)
      - ATP6AP1 binds V-ATPase (Canis familiaris)
        
        V-ATPase [endosome membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Canis familiaris)
        
        V-ATPase [endosome membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)
      - Endosome acidification (Canis familiaris)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Canis familiaris)
        
        V-ATPase [endosome membrane] (Canis familiaris)
        
        ATP6V1 [cytosol] (Canis familiaris)
        
        ATP6V1D [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2QVC0

Gene Names

ATP6V1D

Reference Genes

ENSEMBL:ENSCAFG00000016369

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000016369 ATP6V1D

Other Identifiers

480360

Cfa.1081.1.S1_s_at

GO:0003674

GO:0005575

GO:0006810

GO:0006811

GO:0008150

GO:0022857

GO:0030030

GO:0032991

GO:0033176

GO:0042626

GO:0046961

GO:0055085

GO:1902600

Participant Of

hasComponent

ATP6V1 [cytosol]

Other forms of this molecule

ATP6V1D [plasma membrane]

ATP6V1D [specific granule membrane]

Inferred From

ATP6V1D [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000100554

Ensembl

ENSCAFT00000025963, ENSCAFP00000024103, ENSCAFG00000016369

VGNC

38280

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