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phospho-FYN [plasma membrane]
Stable Identifier
R-CFA-9032530
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
plasma membrane
Synonyms
MyrG-p-Y420-FYN-1, A0A8I3P3X1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
Netrin-1 signaling (Canis familiaris)
DCC mediated attractive signaling (Canis familiaris)
Activation of Cdc42 (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
Activation of Rac1 (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
DCC interacting NCK-1 (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
Phosphorylation of DCC by Fyn (Canis familiaris)
NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
Recruitment and activation of N-WASP by Cdc42 (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
RhoGTPase GEF's recruited to DCC (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
SRC family kinases phosphorylate ERBB2 (Canis familiaris)
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK2 (TRKB) (Canis familiaris)
Activated NTRK2 signals through FYN (Canis familiaris)
NTRK2 activates RAC1 (Canis familiaris)
DOCK3 activates RAC1 (Canis familiaris)
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1:DOCK3 [plasma membrane] (Canis familiaris)
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1 [plasma membrane] (Canis familiaris)
phospho-FYN [plasma membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P3X1
Gene Names
FYN
Reference Genes
ENSEMBL:ENSCAFG00845017640.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845017640.1 FYN
Other Identifiers
475032
Cfa.20235.1.S1_s_at
GO:0001664
GO:0001764
GO:0002376
GO:0003013
GO:0003015
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005768
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0006468
GO:0006886
GO:0007166
GO:0007249
GO:0008092
GO:0008360
GO:0010629
GO:0010976
GO:0014069
GO:0015631
GO:0016004
GO:0016567
GO:0016740
GO:0019899
GO:0023052
GO:0030154
GO:0030163
GO:0030425
GO:0030900
GO:0031175
GO:0031397
GO:0031410
GO:0034330
GO:0035556
GO:0036120
GO:0036211
GO:0042177
GO:0042531
GO:0042802
GO:0043014
GO:0043123
GO:0043226
GO:0043274
GO:0044297
GO:0044325
GO:0045121
GO:0045471
GO:0046875
GO:0048156
GO:0048813
GO:0048856
GO:0048870
GO:0050730
GO:0050798
GO:0050804
GO:0050852
GO:0050877
GO:0050966
GO:0055085
GO:0070851
GO:0071560
GO:0071944
GO:0090314
GO:0097110
GO:0097386
GO:0097718
GO:0098685
GO:0098772
GO:0140096
GO:1900182
GO:1900449
GO:1902951
GO:1904645
GO:1904646
GO:1905664
Participates
as a component of
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1 [plasma membrane] (Canis familiaris)
as a member of
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
as a candidate of
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Canis familiaris)
Other forms of this molecule
phospho-FYN [cytosol]
phospho-FYN [cytosol]
FYN [cytosol]
Inferred From
MyrG-p-Y420-FYN-1 [plasma membrane]
(Homo sapiens)
MyrG-p-Y420-FYN [plasma membrane]
(Homo sapiens)
Modified Residues
Name
N-myristoylglycine at 2 (in Homo sapiens)
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Name
O4'-phospho-L-tyrosine at 420 (in Homo sapiens)
Coordinate
420
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
OpenTargets
ENSG00000010810
Ensembl
ENSCAFG00845017640
,
ENSCAFT00845031308
,
ENSCAFP00845024509
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