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Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
Stable Identifier
R-CFA-8952725
Type
Complex
Species
Canis familiaris
Compartment
lysosomal membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Active MTORC1 binds the ULK1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1 dissociates from ULK complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
PTEN Regulation (Canis familiaris)
Regulation of PTEN gene transcription (Canis familiaris)
MAF1 translocates to the nucleus (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylates MAF1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
MTOR signalling (Canis familiaris)
AKT1S1 (PRAS40) binds mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Energy dependent regulation of mTOR by LKB1-AMPK (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Formation of active mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 binds Ragulator:Rag dimers (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylates AKT1S1 (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1-mediated signalling (Canis familiaris)
Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane]
(Canis familiaris)
SLC38A9 [lysosomal membrane]
(Canis familiaris)
Participates
as an input of
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)
as an output of
SLC38A9 binds Ragulator:Rag dimers (Canis familiaris)
as a component of
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Inferred From
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Homo sapiens)
© 2024
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