Reactome | GAPVD1 [cytosol]

GAPVD1 [cytosol]

Stable Identifier

R-CFA-8871123

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GAPVD1, A0A8I3N6A2

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - Clathrin-mediated endocytosis (Canis familiaris)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GAPVD1 [cytosol] (Canis familiaris)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GAPVD1 [cytosol] (Canis familiaris)
    - RAB5 and GAPVD1 bind AP-2 (Canis familiaris)
      - GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GAPVD1 [cytosol] (Canis familiaris)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
        
        GAPVD1 [cytosol] (Canis familiaris)
  - Rab regulation of trafficking (Canis familiaris)
    - RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
      - RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)
        
        RAB5 GEFs [cytosol] (Canis familiaris)
        
        GAPVD1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N6A2

Gene Names

GAPVD1

Reference Genes

ENSEMBL:ENSCAFG00845009138.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009138.1 GAPVD1

Reference Transcript

RefSeq:XM_014117060.1 GAPVD1

Other Identifiers

480725

CfaAffx.30916.1.S1_at

CfaAffx.30917.1.S1_s_at

CfaAffx.30918.1.S1_s_at

CfaAffx.30919.1.S1_s_at

GO:0005085

GO:0005829

GO:0005886

GO:0016192

GO:0032794

GO:0043087

GO:0051223

GO:0098772

Participates

as a component of

as a member of

RAB5 GEFs [cytosol] (Canis familiaris)

Inferred From

GAPVD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_013972535.1

OpenTargets

ENSG00000165219

Ensembl

ENSCAFT00845016246, ENSCAFG00845009138, ENSCAFP00845012639

Cite Us!