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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Digital Preservation
Contact us
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Table of Contents
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H2AJ [nucleoplasm]
Stable Identifier
R-CFA-8862432
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
H2AFJ, A0A8I3PGL5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Condensation of Prophase Chromosomes (Canis familiaris)
CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PHF8 demethylates histone H4K20me1 (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PLK1 binds phosphorylated condensin II complex (Canis familiaris)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PLK1 hyperphosphorylates Condensin II complex (Canis familiaris)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromosome Maintenance (Canis familiaris)
Telomere Maintenance (Canis familiaris)
Inhibition of DNA recombination at telomere (Canis familiaris)
ATRX:DAXX binds to subtelomeric chromosomal regions (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
DNA Damage/Telomere Stress Induced Senescence (Canis familiaris)
Telomere shortening during replicative exhaustion (Canis familiaris)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Oxidative Stress Induced Senescence (Canis familiaris)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
CDKN2A Gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Canis familiaris)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
CDKN2A Gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Senescence-Associated Secretory Phenotype (SASP) (Canis familiaris)
EHMT1:EHMT2 methylates IL6 promoter (Canis familiaris)
IL6 gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
EHMT1:EHMT2 methylates IL8 promoter (Canis familiaris)
IL8 gene:Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
RMTs methylate histone arginines (Canis familiaris)
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
DNA Repair (Canis familiaris)
Base Excision Repair (Canis familiaris)
Base-Excision Repair, AP Site Formation (Canis familiaris)
Depurination (Canis familiaris)
Cleavage of the damaged purine (Canis familiaris)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Canis familiaris)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Recognition and association of DNA glycosylase with site containing an affected purine (Canis familiaris)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Assembly of the ORC complex at the origin of replication (Canis familiaris)
ORC1 binds to H4K20me2 (Canis familiaris)
H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
H4K20Me2-nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
Epigenetic regulation of gene expression (Canis familiaris)
Negative epigenetic regulation of rRNA expression (Canis familiaris)
NoRC negatively regulates rRNA expression (Canis familiaris)
MBD2 binds methylcytosine in chromatin (Canis familiaris)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
SIRT1 negatively regulates rRNA expression (Canis familiaris)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
eNoSC deacetylates histone H3 (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromatin with acetylated H3 [nucleoplasm] (Canis familiaris)
Nucleosome (H3K9ac, H3K14ac) [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2 methylates histones and DNA (Canis familiaris)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Canis familiaris)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Canis familiaris)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2 recruits DNA methyltransferases (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2 Core:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2 trimethylates histone H3 at lysine-27 (Canis familiaris)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Canis familiaris)
Chromatin with trimethylated H3K27 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K27me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRC2:Chromatin [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Positive epigenetic regulation of rRNA expression (Canis familiaris)
B-WICH complex positively regulates rRNA expression (Canis familiaris)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Canis familiaris)
Nucleosome (H3K9ac) [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Gene Silencing by RNA (Canis familiaris)
Transcriptional regulation by small RNAs (Canis familiaris)
AGO1,2:small RNA complexes interact with chromatin (Canis familiaris)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Chromatin [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RNA Polymerase I Transcription (Canis familiaris)
RNA Polymerase I Promoter Clearance (Canis familiaris)
RNA Polymerase I Promoter Escape (Canis familiaris)
Elongation of pre-rRNA transcript (Canis familiaris)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RNA Polymerase I Promoter Opening (Canis familiaris)
UBF-1 Binds rDNA Promoter (Canis familiaris)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
Binding of AP1 transcriptional activator complexes to CCND1 promoter (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
FOXA1 and GATA3 bind to CCND1 promoter (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Canis familiaris)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me3 [nucleoplasm] (Canis familiaris)
Histone H2A [nucleoplasm] (Canis familiaris)
H2AJ [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PGL5
Gene Names
H2AJ
Reference Genes
BioGPS Gene:486669 H2AJ
ENSEMBL:ENSCAFG00845021375.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845021375.1 H2AJ
KEGG Gene (Canis lupus familiaris):486669 H2AJ
Monarch:486669 H2AJ
NCBI Gene:486669 H2AJ
Reference Transcript
RefSeq:XM_543796.5 H2AJ
Other Identifiers
486669
CfaAffx.20099.1.S1_s_at
GO:0000786
GO:0003677
GO:0005198
GO:0005634
GO:0005694
GO:0030527
GO:0043226
GO:0046982
Participates
as a candidate of
Histone H2A [nucleoplasm] (Canis familiaris)
Inferred From
H2AFJ [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_543796.1
OpenTargets
ENSG00000246705
Ensembl
ENSCAFP00845029546
,
ENSCAFT00845037709
,
ENSCAFG00845021375
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