Reactome | HAUS6 [cytosol]

HAUS6 [cytosol]

Stable Identifier

R-CFA-8855196

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

HAUS6, A0A8I3NV93

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Canis familiaris)

- Cilium Assembly (Canis familiaris)
  - Anchoring of the basal body to the plasma membrane (Canis familiaris)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Canis familiaris)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - C2CD3 binds the mother centriole (Canis familiaris)
      - mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Canis familiaris)
      - basal body:transition zone proteins [cytosol] (Canis familiaris)
        
        basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
        
        basal body:transition zone proteins [cytosol] (Canis familiaris)
        
        basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - CP110 and CEP97 dissociate from the centriole (Canis familiaris)
      - basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - MARK4 binds ODF2 in the centriole (Canis familiaris)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
        
        basal body:transition zone proteins [cytosol] (Canis familiaris)
        
        basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - Recruitment of transition zone proteins (Canis familiaris)
      - basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - basal body:transition zone proteins [cytosol] (Canis familiaris)
        
        basal body [cytosol] (Canis familiaris)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
    - The distal appendage proteins recruit TTBK2 (Canis familiaris)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
        
        mother centriole:C2CD3 [cytosol] (Canis familiaris)
        
        mother centriole [cytosol] (Canis familiaris)
        
        HAUS complex [cytosol] (Canis familiaris)
        
        HAUS6 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NV93

Gene Names

HAUS6

Reference Genes

BioGPS Gene:100856608 HAUS6

ENSEMBL:ENSCAFG00845014208.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845014208.1 HAUS6

KEGG Gene (Canis lupus familiaris):100856608 HAUS6

Monarch:100856608 HAUS6

NCBI Gene:100856608 HAUS6

Reference Transcript

RefSeq:XM_003639358.3 HAUS6

Other Identifiers

100856608

CfaAffx.3303.1.S1_s_at

GO:0005813

GO:0005815

GO:0005856

GO:0007010

GO:0007059

GO:0007098

GO:0043226

GO:0051225

GO:0070652

GO:1990498

Participates

as a component of

HAUS complex [cytosol] (Canis familiaris)

Inferred From

HAUS6 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003639406.1

OpenTargets

ENSG00000147874

Ensembl

ENSCAFP00845020002, ENSCAFT00845025411, ENSCAFG00845014208

Cite Us!