Reactome | LOC119876809 [extracellular region]

LOC119876809 [extracellular region]

Stable Identifier

R-CFA-877338

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

IFNA5, A0A8I3NZD7

Locations in the PathwayBrowser

Expand all

Immune System (Canis familiaris)

- Cytokine Signaling in Immune system (Canis familiaris)
  - Interferon Signaling (Canis familiaris)
    - Interferon alpha/beta signaling (Canis familiaris)
      - Activation of JAK kinases (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Formation of p-STAT1 homodimer (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - IFN alpha/beta binds to IFNAR2 (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Phosphorylation of INFAR1 by TYK2 (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Phosphorylation of STAT2 (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Recruitment of IFNAR1 (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Recruitment of STAT2 to p-IFNAR1 (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Regulation of IFNA/IFNB signaling (Canis familiaris)
        
        Dephosphorylation of JAK1 by SHP1 (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        Dephosphorylation of STAT1 by SHP2 (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        Dephosphorylation of TYK2 by PTP1B (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
      - Release of p-STAT2:p-STAT1 dimer (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Canis familiaris)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Canis familiaris)
        
        IFNA [extracellular region] (Canis familiaris)
        
        Homologues of IFNA5 [extracellular region] (Canis familiaris)
        
        LOC119876809 [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NZD7

Gene Names

LOC119876809

Reference Genes

ENSEMBL:ENSCAFG00845016083.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845016083.1 LOC119876809

Other Identifiers

100683045

119876809

GO:0005126

GO:0005576

GO:0006952

Participates

as a member of

Homologues of IFNA5 [extracellular region] (Canis familiaris)

Other forms of this molecule

LOC119876809 [extracellular region]

Inferred From

IFNA5 [extracellular region] (Homo sapiens)

Cross References

Ensembl

ENSCAFT00845028608, ENSCAFP00845022513, ENSCAFG00845016083

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