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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
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COVID-19 Disease Pathways
Docs
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PIK3CB [cytosol]
Stable Identifier
R-CFA-74788
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
PIK3CB, A0A8I3PWT3
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
RET signaling (Canis familiaris)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
Tie2 Signaling (Canis familiaris)
Interaction of Tie2 and p85 of PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85 bound to Tie2 [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
GPVI-mediated activation cascade (Canis familiaris)
GPVI stimulates PI3K beta, gamma (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Canis familiaris)
PI3K alpha, beta, gamma [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Recruitment of PI3K to plasma membrane (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
14-3-3 zeta binding allows recruitment of PI3K (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Regulation of signaling by CBL (Canis familiaris)
CBL ubiquitinates PI3K (Canis familiaris)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
K63polyUb-p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
K63polyUb-PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Canis familiaris)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85-containing Class 1A PI3Ks [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p85 regulatory unit of PI3K binds p-6Y-SYK (Canis familiaris)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
Role of LAT2/NTAL/LAB on calcium mobilization (Canis familiaris)
PI3K associates with phosphorylated GAB2 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Role of phospholipids in phagocytosis (Canis familiaris)
PI3K binds to p-6Y-SYK (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Phospholipid metabolism (Canis familiaris)
PI Metabolism (Canis familiaris)
Synthesis of PIPs at the plasma membrane (Canis familiaris)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Canis familiaris)
PIK3C(1) [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PIK3CB:PIK3R2 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PIK3CB:PIK3R3 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)
PIK3(2) [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PIK3CB:PIK3R2 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PIK3CB:PIK3R3 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS:GTP binds PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p21 RAS:GTP:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by Erythropoietin (Canis familiaris)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Canis familiaris)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K bound to EPOR [plasma membrane] (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:PI3K [plasma membrane] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Canis familiaris)
PI3K alpha, gamma [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ALK (Canis familiaris)
Active ALK recruits PI3K (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
PI3K/AKT activation (Canis familiaris)
Active IRS recruits PI3K to the plasma membrane and activates it (Canis familiaris)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K produces PIP3 and other phosphatidyl inositides (Canis familiaris)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
PI3-kinase binds to the active receptor (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
p-AXL binds PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-catalytic subunit [cytosol] (Canis familiaris)
PIK3CB [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PWT3
Gene Names
PIK3CB
Reference Genes
ENSEMBL:ENSCAFG00845025921.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025921.1 PIK3CB
Reference Transcript
RefSeq:XM_014106660.1 PIK3CB
RefSeq:XM_534280.5 PIK3CB
Other Identifiers
477085
Cfa.20019.1.S1_s_at
CfaAffx.12224.1.S1_at
GO:0000166
GO:0001952
GO:0002376
GO:0003376
GO:0003824
GO:0005524
GO:0005634
GO:0005654
GO:0005730
GO:0005943
GO:0006629
GO:0007155
GO:0010595
GO:0010628
GO:0012501
GO:0014065
GO:0016301
GO:0016303
GO:0016310
GO:0016740
GO:0023052
GO:0030496
GO:0033031
GO:0035004
GO:0035022
GO:0036092
GO:0043226
GO:0043231
GO:0043491
GO:0045429
GO:0046854
GO:0046934
GO:0048015
GO:0048856
GO:0048870
GO:0051898
GO:0106310
GO:0140096
GO:1900747
GO:1903671
Participates
as a component of
K63polyUb-PI3K beta [cytosol] (Canis familiaris)
PI3K beta [cytosol] (Canis familiaris)
PIK3CB:PIK3R2 [cytosol] (Canis familiaris)
PIK3CB:PIK3R1 [cytosol] (Canis familiaris)
PIK3CB:PIK3R3 [cytosol] (Canis familiaris)
as a member of
PI3K-catalytic subunit [cytosol] (Canis familiaris)
Inferred From
PIK3CB [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_534280.2
,
XP_013962135.1
OpenTargets
ENSG00000051382
Ensembl
ENSCAFT00845045772
,
ENSCAFG00845025921
,
ENSCAFP00845035926
© 2024
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