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PI3K-regulatory subunit [cytosol]
Stable Identifier
R-CFA-74688
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
Tie2 Signaling (Canis familiaris)
Interaction of Tie2 and p85 of PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p85 bound to Tie2 [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Recruitment of PI3K to plasma membrane (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p85 regulatory unit of PI3K binds p-6Y-SYK (Canis familiaris)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
Role of LAT2/NTAL/LAB on calcium mobilization (Canis familiaris)
PI3K associates with phosphorylated GAB2 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Role of phospholipids in phagocytosis (Canis familiaris)
PI3K binds to p-6Y-SYK (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K:p-6Y-SYK [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K bound to TRAT [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS:GTP binds PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p21 RAS:GTP:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ALK (Canis familiaris)
Active ALK recruits PI3K (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)
Active ALK:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
PI3K/AKT activation (Canis familiaris)
Active IRS recruits PI3K to the plasma membrane and activates it (Canis familiaris)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K produces PIP3 and other phosphatidyl inositides (Canis familiaris)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
PI3-kinase binds to the active receptor (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
p-AXL binds PI3K (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Canis familiaris)
PI3K [cytosol] (Canis familiaris)
PI3K-regulatory subunit [cytosol] (Canis familiaris)
Participants
members
PIK3R1 [cytosol]
(Canis familiaris)
PIK3R2 [cytosol]
(Canis familiaris)
Participates
as a component of
PI3K [cytosol] (Canis familiaris)
Inferred From
PI3K-regulatory subunit [cytosol]
(Homo sapiens)
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