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EIF4A1 [cytosol]
Stable Identifier
R-CFA-72573
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
EIF4A1, A0A8I3S757
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
ISG15 antiviral mechanism (Canis familiaris)
Competitive inhibition of translation initiation by ISGylated 4EHP (Canis familiaris)
EIF4F [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4F:mRNA [cytosol] (Canis familiaris)
EIF4F [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Metabolism of RNA (Canis familiaris)
Deadenylation-dependent mRNA decay (Canis familiaris)
Deadenylation of mRNA (Canis familiaris)
CCR4-NOT complex deadenylates mRNA (Canis familiaris)
Partially Deadenylated mRNA Complex [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
PAN2-PAN3 complex partially deadenylates mRNA (Canis familiaris)
Partially Deadenylated mRNA Complex [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Translatable mRNA Complex [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
PARN deadenylates mRNA (Canis familiaris)
Partially Deadenylated mRNA Complex [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4A [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Translation (Canis familiaris)
Eukaryotic Translation Initiation (Canis familiaris)
Cap-dependent Translation Initiation (Canis familiaris)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Canis familiaris)
Cap-bound mRNA is activated by helicases (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4F:mRNP [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Formation of the cap-binding eIF4F complex (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Translation initiation complex formation (Canis familiaris)
Formation of translation initiation complexes containing mRNA that does not circularize (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
GTP hydrolysis and joining of the 60S ribosomal subunit (Canis familiaris)
eIF2:GTP is hydrolyzed, eIFs are released (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Ribosomal scanning and start codon recognition (Canis familiaris)
Ribosomal scanning (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
Start codon recognition (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
L13a-mediated translational silencing of Ceruloplasmin expression (Canis familiaris)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
eIF4F [cytosol] (Canis familiaris)
eIF4A subunits complex [cytosol] (Canis familiaris)
EIF4A1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3S757
Gene Names
EIF4A1
Reference Genes
BioGPS Gene:100688577 EIF4A1
ENSEMBL:ENSCAFG00845023393.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845023393.1 EIF4A1
KEGG Gene (Canis lupus familiaris):100688577 EIF4A1
Monarch:100688577 EIF4A1
NCBI Gene:100688577 EIF4A1
Reference Transcript
RefSeq:NM_001251942.1 EIF4A1
Other Identifiers
100688577
Cfa.5726.1.A1_s_at
GO:0000166
GO:0002181
GO:0002183
GO:0003676
GO:0003723
GO:0003724
GO:0003725
GO:0003743
GO:0003824
GO:0004386
GO:0005524
GO:0005737
GO:0006412
GO:0006413
GO:0016787
GO:0045182
GO:0140098
GO:0140657
Participates
as a component of
eIF4A subunits complex [cytosol] (Canis familiaris)
as a member of
eIF4A [cytosol] (Canis familiaris)
Inferred From
EIF4A1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001238871.1
OpenTargets
ENSG00000161960
Ensembl
ENSCAFP00845032483
,
ENSCAFT00845041428
,
ENSCAFG00845023393
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