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MCM6 [nucleoplasm]
Stable Identifier
R-CFA-68553
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
MCM6, A0A8I3N2T8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
Activation of ATR in response to replication stress (Canis familiaris)
Activation of claspin (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Loading of claspin onto DNA during replication origin firing (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1/S Transition (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Mcm4,6,7 trimer forms and associates with the replication fork (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Formation of MCM2-7 complex (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM4, MCM6 and MCM7 form a heterotrimer (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Mcm4,6,7 trimer forms and associates with the replication fork (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
MCM6 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N2T8
Gene Names
MCM6
Reference Genes
BioGPS Gene:476131 MCM6
ENSEMBL:ENSCAFG00845009951.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009951.1 MCM6
KEGG Gene (Canis lupus familiaris):476131 MCM6
Monarch:476131 MCM6
NCBI Gene:476131 MCM6
Reference Transcript
RefSeq:XM_533338.5 MCM6
Other Identifiers
476131
Cfa.2489.1.S1_at
CfaAffx.8672.1.S1_s_at
GO:0000228
GO:0003677
GO:0003678
GO:0003697
GO:0003824
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0006260
GO:0006268
GO:0006270
GO:0032508
GO:0042555
GO:0042802
GO:0043226
GO:0071162
GO:0140097
GO:0140657
Participates
as an input of
MCM4, MCM6 and MCM7 form a heterotrimer (Canis familiaris)
as a component of
MCM4:MCM6:MCM7 [nucleoplasm] (Canis familiaris)
Inferred From
MCM6 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_533338.3
OpenTargets
ENSG00000076003
Ensembl
ENSCAFT00845017492
,
ENSCAFG00845009951
,
ENSCAFP00845013615
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