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CCNE2 [nucleoplasm]
Stable Identifier
R-CFA-68367
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
CCNE2, A0A8I3NWC1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G1/S DNA Damage Checkpoints (Canis familiaris)
p53-Dependent G1/S DNA damage checkpoint (Canis familiaris)
p53-Dependent G1 DNA Damage Response (Canis familiaris)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G0 and Early G1 (Canis familiaris)
p107 (RBL1) binds CyclinE/A:CDK2 (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
RBL1:Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
RBL1:E2F4:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
p130 (RBL2) binds Cyclin E/A:CDK2 (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
RBL2:Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E/A [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
G1 Phase (Canis familiaris)
Cyclin D associated events in G1 (Canis familiaris)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
G1/S Transition (Canis familiaris)
Cyclin E associated events during G1/S transition (Canis familiaris)
Association of Rb with Cyclin E:Cdk2 complexes (Canis familiaris)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
CAK-mediated phosphorylation of Cyclin E:Cdk2 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes (Canis familiaris)
Cyclin E:CDK2-mediated phosphorylation of RB1 (Canis familiaris)
CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
SCF(Skp2)-mediated degradation of p27/p21 (Canis familiaris)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Canis familiaris)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Ubiquitination of phospho-p27/p21 (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Translocation of Cyclin E:Cdk2 complex to the nucleus (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
S Phase (Canis familiaris)
Cyclin A:Cdk2-associated events at S phase entry (Canis familiaris)
SCF(Skp2)-mediated degradation of p27/p21 (Canis familiaris)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Canis familiaris)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Ubiquitination of phospho-p27/p21 (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Canis familiaris)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Canis familiaris)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cdc6 protein is phosphorylated by CDK (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
DNA Damage/Telomere Stress Induced Senescence (Canis familiaris)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cdc6 protein is phosphorylated by CDK (Canis familiaris)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E:p-T160-CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Transcription of Cell Cycle Genes (Canis familiaris)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Canis familiaris)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Canis familiaris)
CCNE:CDK2 [nucleoplasm] (Canis familiaris)
Cyclin E [nucleoplasm] (Canis familiaris)
CCNE2 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NWC1
Gene Names
CCNE2
Reference Genes
ENSEMBL:ENSCAFG00845016153.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845016153.1 CCNE2
Other Identifiers
487057
Cfa.344.1.A1_at
CfaAffx.14834.1.S1_at
GO:0000723
GO:0006260
GO:0006270
GO:0007059
GO:0007129
GO:0016538
GO:0022414
GO:0032200
GO:0032880
GO:0051726
GO:0070192
GO:0097135
GO:0098772
GO:0140013
Participates
as a candidate of
Cyclin E [nucleoplasm] (Canis familiaris)
as a member of
Cyclin E [nucleoplasm] (Canis familiaris)
Other forms of this molecule
CCNE2 [cytosol]
Inferred From
CCNE2 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000175305
Ensembl
ENSCAFT00845028743
,
ENSCAFP00845022624
,
ENSCAFG00845016153
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