Reactome | RPTN [cytosol]

RPTN [cytosol]

Stable Identifier

R-CFA-6814185

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

RPTN, A0A8I3PMI7

Locations in the PathwayBrowser

Expand all

Developmental Biology (Canis familiaris)

- Keratinization (Canis familiaris)
  - Formation of the cornified envelope (Canis familiaris)
    - CASP14 cleaves filaggrin (Canis familiaris)
      - Late cornified envelope [plasma membrane] (Canis familiaris)
        
        Cornified envelope:CDSN [plasma membrane] (Canis familiaris)
        
        Cornified envelope [plasma membrane] (Canis familiaris)
        
        Early cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
      - Mature cornified envelope [plasma membrane] (Canis familiaris)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Canis familiaris)
        
        No FGN-Cornified envelope [plasma membrane] (Canis familiaris)
        
        No FGN-late cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
    - CDSN binds the cornified envelope (Canis familiaris)
      - Cornified envelope [plasma membrane] (Canis familiaris)
        
        Early cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
      - Cornified envelope:CDSN [plasma membrane] (Canis familiaris)
        
        Cornified envelope [plasma membrane] (Canis familiaris)
        
        Early cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
    - Lamellar bodies bind the early cornified envelope (Canis familiaris)
      - Cornified envelope [plasma membrane] (Canis familiaris)
        
        Early cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
      - Early cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)
    - Plasma membrane resorption (Canis familiaris)
      - Mature cornified envelope [plasma membrane] (Canis familiaris)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Canis familiaris)
        
        No FGN-Cornified envelope [plasma membrane] (Canis familiaris)
        
        No FGN-late cornified envelope [plasma membrane] (Canis familiaris)
        
        Minor CE proteins [cytosol] (Canis familiaris)
        
        RPTN [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PMI7

Gene Names

RPTN

Reference Genes

ENSEMBL:ENSCAFG00845025826.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025826.1 RPTN

Other Identifiers

100685981

CfaAffx.20102.1.S1_at

CfaAffx.20103.1.S1_at

CfaAffx.20103.1.S1_s_at

GO:0005509

GO:0046872

GO:0046914

Participates

as a member of

Minor CE proteins [cytosol] (Canis familiaris)

Other forms of this molecule

RPTN [cornified envelope]

Inferred From

RPTN [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000215853

Ensembl

ENSCAFP00845035732, ENSCAFG00845025826, ENSCAFT00845045553

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