Reactome | COPZ2 [transport vesicle]

COPZ2 [transport vesicle]

Stable Identifier

R-CFA-6808760

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

transport vesicle

Synonyms

COPZ2, A0A8I3NPT5

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPI-mediated anterograde transport (Canis familiaris)
      - ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
    - Golgi-to-ER retrograde transport (Canis familiaris)
      - COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        coatomer [transport vesicle] (Canis familiaris)
        
        tetrameric coatomer complex [transport vesicle] (Canis familiaris)
        
        COPZ2 [transport vesicle] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NPT5

Gene Names

COPZ2

Reference Genes

ENSEMBL:ENSCAFG00845016156.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845016156.1 COPZ2

Reference Transcript

RefSeq:XM_005624610.1 COPZ2

Other Identifiers

491050

Cfa.20974.1.S1_at

CfaAffx.25723.1.S1_s_at

GO:0000139

GO:0005737

GO:0005794

GO:0006890

GO:0015031

GO:0016020

GO:0016192

GO:0030126

GO:0030663

GO:0031410

GO:0043226

Participates

as a component of

tetrameric coatomer complex [transport vesicle] (Canis familiaris)

Other forms of this molecule

COPZ2 [endoplasmic reticulum membrane]

COPZ2 [cytosol]

COPZ2 [Golgi membrane]

Inferred From

COPZ1,2 [transport vesicle] (Homo sapiens)

COPZ2 [transport vesicle] (Homo sapiens)

Cross References

RefSeq

XP_005624667.1

OpenTargets

ENSG00000005243

Ensembl

ENSCAFT00845028733, ENSCAFP00845022614, ENSCAFG00845016156

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