Reactome | XPA [nucleoplasm]

XPA [nucleoplasm]

Stable Identifier

R-CFA-67437

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

XPA, A0A8I3NWC3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A8I3NWC3

Gene Names

XPA

Reference Genes

BioGPS Gene:481623 XPA

ENSEMBL:ENSCAFG00845014486.1

KEGG:cfa:481623 XPA

Monarch:481623 XPA

NCBI Gene:481623 XPA

UCSC:A0A8I3NWC3 XPA

Reference Transcript

RefSeq:XM_538745.5 XPA

Other Identifiers

481623

Cfa.11211.1.A1_at

CfaAffx.4557.1.S1_s_at

GO:0003677

GO:0003684

GO:0005634

GO:0005654

GO:0005662

GO:0006281

GO:0006289

GO:0009650

GO:0019904

GO:0034504

GO:0042803

GO:0043226

GO:0045171

GO:1990837

Participates

as an output of

3' incision by ERCC5 (XPG) in TC-NER (Canis familiaris)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Canis familiaris)

as an input of

Assembly of the pre-incision complex in TC-NER (Canis familiaris)
Recruitment of XPA and release of CAK (Canis familiaris)

as a component of

Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Canis familiaris)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Canis familiaris)
TC-NER pre-incision complex [nucleoplasm] (Canis familiaris)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Canis familiaris)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Canis familiaris)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Canis familiaris)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Canis familiaris)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Canis familiaris)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)

Inferred From

XPA [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845025919, ENSCAFG00845014486, ENSCAFP00845020434