Reactome | NDUFA3 [mitochondrial inner membrane]

NDUFA3 [mitochondrial inner membrane]

Stable Identifier

R-CFA-60180

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial inner membrane

Synonyms

NDUFA3, A0A8I3MJP7

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- Aerobic respiration and respiratory electron transport (Canis familiaris)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
    - Respiratory electron transport (Canis familiaris)
      - Complex I biogenesis (Canis familiaris)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA3 [mitochondrial inner membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MJP7

Gene Names

NDUFA3

Reference Genes

BioGPS Gene:611480 NDUFA3

ENSEMBL:ENSCAFG00845003928.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845003928.1 NDUFA3

KEGG Gene (Canis lupus familiaris):611480 NDUFA3

Monarch:611480 NDUFA3

NCBI Gene:611480 NDUFA3

Reference Transcript

RefSeq:XM_005616133.2 NDUFA3

Other Identifiers

611480

Cfa.16049.1.S1_at

CfaAffx.4928.1.S1_x_at

GO:0005739

GO:0005743

GO:0005747

GO:0016020

GO:0043226

GO:0070469

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Canis familiaris)

Inferred From

NDUFA3 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

XP_005616190.1

OpenTargets

ENSG00000170906

Ensembl

ENSCAFG00845003928, ENSCAFT00845007060, ENSCAFP00845005631