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MAPK3 [cytosol]
Stable Identifier
R-CFA-59284
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
MAPK3, A0A8I3RQD0
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
F2R:ARRB1 binds MAPKs, SRC-1 (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
F2R:ARRB2 binds MAPKs, SRC-1 (Canis familiaris)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
SRC-1 bound to ARRB2 is not activated (Canis familiaris)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Growth hormone receptor signaling (Canis familiaris)
Lyn activates ERK (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
ISG15 antiviral mechanism (Canis familiaris)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Canis familiaris)
ISG15 targets [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
ISGylated host proteins [cytosol] (Canis familiaris)
ISG15 targets [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Interferon gamma signaling (Canis familiaris)
IFNG signaling activates MAPKs (Canis familiaris)
JAK1-activated RAF1 phosphorylates MAPKs (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF-independent MAPK1/3 activation (Canis familiaris)
Cytosolic DUSPs dephosphorylate MAPKs (Canis familiaris)
MAPK monomers and dimers [cytosol] (Canis familiaris)
MAPK3 dimer [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
Cytosolic DUSPs dephosphorylate MAPKs (Canis familiaris)
MAPK monomers and dimers [cytosol] (Canis familiaris)
MAPK3 dimer [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
Signal attenuation (Canis familiaris)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Canis familiaris)
MAPK3,(MAPK1) [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Canis familiaris)
MAPK3,(MAPK1) [cytosol] (Canis familiaris)
MAPK3 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3RQD0
Gene Names
MAPK3
Reference Genes
ENSEMBL:ENSCAFG00845002016.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845002016.1 MAPK3
Other Identifiers
100855877
CfaAffx.26169.1.S1_at
CfaAffx.28981.1.S1_s_at
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006468
GO:0007010
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0031410
GO:0032872
GO:0036211
GO:0043226
GO:0051493
GO:0072584
GO:0090170
GO:0140096
GO:2000641
Participates
as a member of
ISG15 targets [cytosol] (Canis familiaris)
MAPK3,(MAPK1) [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
as a component of
MAPK3 dimer [cytosol] (Canis familiaris)
Other forms of this molecule
phospho-MAPK3 [cytosol]
MAPK3 [nucleoplasm]
phospho-MAPK3 [cytosol]
phospho-MAPK3 [nucleoplasm]
Inferred From
MAPK3 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000102882
Ensembl
ENSCAFP00845002814
,
ENSCAFT00845003544
,
ENSCAFG00845002016
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