Reactome | STX5 [ER to Golgi transport vesicle membrane]

STX5 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-CFA-5689838

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

ER to Golgi transport vesicle membrane

Synonyms

STX5, E2R287

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPII-mediated vesicle transport (Canis familiaris)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        CSNK1D phosphorylates SEC23 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        Nucleotide exchange on RAB1 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPII-mediated vesicle transport (Canis familiaris)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
      - COPII coat binds TRAPPCII and RAB1:GDP (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
      - CSNK1D phosphorylates SEC23 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
      - Nucleotide exchange on RAB1 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
      - Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        GOSR2,STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        STX5 [ER to Golgi transport vesicle membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2R287

Gene Names

STX5

Reference Genes

BioGPS Gene:483779 STX5

ENSEMBL:ENSCAFG00000015540

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000015540 STX5

KEGG Gene (Canis lupus familiaris):483779 STX5

Monarch:483779 STX5

NCBI Gene:483779 STX5

Reference Transcript

Other Identifiers

483779

CfaAffx.23837.1.S1_s_at

GO:0000139

GO:0000149

GO:0003674

GO:0005484

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0005829

GO:0006810

GO:0006886

GO:0006888

GO:0006906

GO:0008150

GO:0009056

GO:0012505

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0030674

GO:0031201

GO:0031982

GO:0032991

GO:0034498

GO:0042147

GO:0043226

GO:0045732

GO:0047485

GO:0048278

GO:0061024

GO:0090166

GO:1903358

Participant Of

hasMember

GOSR2,STX5 [ER to Golgi transport vesicle membrane]

Other forms of this molecule

STX5 [cytosol]

STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane]

STX5 [endoplasmic reticulum membrane]

STX5 [Golgi membrane]

Inferred From

STX5 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

XP_005631656.1, XP_853496.1, XP_013976547.1

OpenTargets

ENSG00000162236

Ensembl

ENSCAFT00000024637, ENSCAFP00000022858, ENSCAFG00000015540

VGNC

46957

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