Reactome | LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane]

LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-CFA-5689808

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

GPI-FOLR1, A0A8I3N9V0

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        COPII-mediated vesicle transport (Canis familiaris)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPI-mediated anterograde transport (Canis familiaris)
      - ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
      - ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
    - COPII-mediated vesicle transport (Canis familiaris)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LOC609612 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N9V0

Gene Names

LOC609612

Reference Genes

BioGPS Gene:609612 LOC609612

ENSEMBL:ENSCAFG00845010357.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845010357.1 LOC609612

KEGG Gene (Canis lupus familiaris):609612 LOC609612

Monarch:609612 LOC609612

NCBI Gene:609612 LOC609612

Reference Transcript

Other Identifiers

609612

CfaAffx.9619.1.S1_s_at

CfaAffx.9623.1.S1_at

GO:0001947

GO:0003147

GO:0003253

GO:0005542

GO:0005634

GO:0005886

GO:0006575

GO:0006766

GO:0009897

GO:0015884

GO:0016323

GO:0016324

GO:0017015

GO:0023052

GO:0030154

GO:0031103

GO:0038024

GO:0043226

GO:0046655

GO:0048678

GO:0048856

GO:0048870

GO:0060828

GO:0061626

GO:0061713

GO:0061714

GO:0071231

Participates

as a member of

GPI-CD59, GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

Other forms of this molecule

LOC609612 [ER to Golgi transport vesicle membrane]

LOC609612 [endoplasmic reticulum membrane]

LOC609612 [transport vesicle]

LOC609612 [Golgi membrane]

Inferred From

GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 201 (in Homo sapiens)

Coordinate

201

Modification

GPI-anchor amidated amino acid carboxyl end residue(1−)

PsiMod Name

L-serine amide

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-serine amide.

Cross References

RefSeq

XP_005633611.1, XP_851993.1

Ensembl

ENSCAFP00845014229, ENSCAFT00845018242, ENSCAFG00845010357

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