Reactome | GEN1 [nucleoplasm]

GEN1 [nucleoplasm]

Stable Identifier

R-CFA-5686495

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

GEN1, A0A8I3P1R2

Locations in the PathwayBrowser

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DNA Repair (Canis familiaris)

- DNA Double-Strand Break Repair (Canis familiaris)
  - Homology Directed Repair (Canis familiaris)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Canis familiaris)
      - HDR through Homologous Recombination (HRR) (Canis familiaris)
        
        Resolution of D-Loop Structures (Canis familiaris)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Canis familiaris)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Canis familiaris)
        
        SLX1A:SLX4:MUS81:EME1,(MUS81:EME2),GEN1 [nucleoplasm] (Canis familiaris)
        
        GEN1 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P1R2

Gene Names

GEN1

Reference Genes

BioGPS Gene:482980 GEN1

ENSEMBL:ENSCAFG00845017081.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845017081.1 GEN1

Monarch:482980 GEN1

NCBI Gene:482980 GEN1

Reference Transcript

Other Identifiers

482980

CfaAffx.6562.1.S1_at

GO:0000278

GO:0000287

GO:0000400

GO:0000724

GO:0003677

GO:0003824

GO:0004518

GO:0004519

GO:0005813

GO:0005815

GO:0005856

GO:0006260

GO:0006281

GO:0006310

GO:0006974

GO:0007010

GO:0007059

GO:0008821

GO:0010824

GO:0016787

GO:0017108

GO:0023052

GO:0031297

GO:0042803

GO:0043226

GO:0046872

GO:0071139

GO:0071140

GO:0090267

GO:0140014

GO:0140097

Participates

as a member of

SLX1A:SLX4:MUS81:EME1,(MUS81:EME2),GEN1 [nucleoplasm] (Canis familiaris)

Inferred From

GEN1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_013975813.1, XP_540093.2

OpenTargets

ENSG00000178295

Ensembl

ENSCAFP00845023725, ENSCAFT00845030254, ENSCAFG00845017081

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