Reactome | CNKSR1 [cytosol]

CNKSR1 [cytosol]

Stable Identifier

R-CFA-5672629

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

CNKSR1, A0A8I3NR25

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- MAPK family signaling cascades (Canis familiaris)
  - MAPK1/MAPK3 signaling (Canis familiaris)
    - RAF/MAP kinase cascade (Canis familiaris)
      - MAP2K and MAPK activation (Canis familiaris)
        
        Dissociation of RAS:RAF complex (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        MAP2Ks phosphorylate MAPKs (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        RAF phosphorylates MAP2K dimer (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        Single mechanism MAPK inhibitors bind phosphorylated MAPK (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
        
        RAF/MAPK scaffolds [cytosol] (Canis familiaris)
        
        CNKSR1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NR25

Gene Names

CNKSR1

Reference Genes

ENSEMBL:ENSCAFG00845012989.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845012989.1 CNKSR1

Other Identifiers

100855977

CfaAffx.19586.1.S1_at

GO:0005515

GO:0005938

GO:0030674

GO:0060090

Participates

as a candidate of

RAF/MAPK scaffolds [cytosol] (Canis familiaris)

Inferred From

CNKSR1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000142675

Ensembl

ENSCAFT00845023161, ENSCAFP00845018161, ENSCAFG00845012989

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