Reactome | TNFSF14 [plasma membrane]

TNFSF14 [plasma membrane]

Stable Identifier

R-CFA-5667149

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

TNFSF14, J9P753

Locations in the PathwayBrowser

Expand all

Immune System (Canis familiaris)

- Cytokine Signaling in Immune system (Canis familiaris)
  - TNFR2 non-canonical NF-kB pathway (Canis familiaris)
    - K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Canis familiaris)
      - TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
      - TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
    - Protesomal degradation of K48polyUb-TRAF3 (Canis familiaris)
      - TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
      - TNFSF:TNFRSF heterotrimer:TRAF2:K63polyUb-cIAP1,2:K48polyUb-TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
    - TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Canis familiaris)
      - 2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
      - TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
    - TNFs bind their physiological receptors (Canis familiaris)
      - TNFRSF6B binds TNFSF6,14,15 (Canis familiaris)
        
        TNFRSF6B:TNFSF6,14,15 [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
    - TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Canis familiaris)
      - Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
      - TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)
    - cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Canis familiaris)
      - TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Canis familiaris)
        
        TNFA:TNFR2,BAFF:BAFFR,TWEAK:Fn14,Lymphotoxin:LTBR,RANKL:RANK,CD40L:CD40 [plasma membrane] (Canis familiaris)
        
        3xLTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        LTBR:lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        lymphotoxin,TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 trimer [plasma membrane] (Canis familiaris)
        
        TNFSF14 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9P753

Gene Names

TNFSF14

Reference Genes

BioGPS Gene:611306 TNFSF14

ENSEMBL:ENSCAFG00845010429.1

KEGG:cfa:611306 TNFSF14

Monarch:611306 TNFSF14

NCBI Gene:611306 TNFSF14

UCSC:J9P753 TNFSF14

Reference Transcript

RefSeq:NM_001284494.1 TNFSF14

Other Identifiers

611306

CfaAffx.28466.1.S1_at

GO:0002376

GO:0005102

GO:0005125

GO:0005164

GO:0005615

GO:0006955

GO:0007165

GO:0010818

GO:0010820

GO:0016020

GO:0031295

GO:0043027

GO:0045663

GO:0048018

GO:0048870

GO:0071260

GO:0098772

GO:1901224

GO:1901741

Participates

as an input of

TNFRSF6B binds TNFSF6,14,15 (Canis familiaris)

as a component of

Inferred From

TNFSF6,14,15 [plasma membrane] (Homo sapiens)

TNFSF14 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001271423.1

ENSEMBL

ENSCAFT00845018372, ENSCAFP00845014343

VGNC

47670

Cite Us!