Reactome | SPRED3 [plasma membrane]

SPRED3 [plasma membrane]

Stable Identifier

R-CFA-5658223

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

SPRED3, A0A8I3MRJ5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- MAPK family signaling cascades (Canis familiaris)
  - MAPK1/MAPK3 signaling (Canis familiaris)
    - RAF/MAP kinase cascade (Canis familiaris)
      - Regulation of RAS by GAPs (Canis familiaris)
        
        NF1 is degraded by the proteasome (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        SPRED dimer:ub-NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        RAS GAPs bind RAS:GTP (Canis familiaris)
        
        RAS GAPs [cytosol] (Canis familiaris)
        
        SPRED dimer:NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        p21 RAS:GTP:RAS GAPs [plasma membrane] (Canis familiaris)
        
        RAS GAPs [cytosol] (Canis familiaris)
        
        SPRED dimer:NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        RAS GAPs stimulate RAS GTPase activity (Canis familiaris)
        
        RAS GAPs [cytosol] (Canis familiaris)
        
        SPRED dimer:NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        p21 RAS:GTP:RAS GAPs [plasma membrane] (Canis familiaris)
        
        RAS GAPs [cytosol] (Canis familiaris)
        
        SPRED dimer:NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        SPRED dimer binds NF1 (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)
        
        SPRED dimer:NF1 [plasma membrane] (Canis familiaris)
        
        SPRED dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 dimer [plasma membrane] (Canis familiaris)
        
        SPRED3 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MRJ5

Gene Names

SPRED3

Reference Genes

BioGPS Gene:612575 SPRED3

ENSEMBL:ENSCAFG00845005619.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845005619.1 SPRED3

KEGG Gene (Canis lupus familiaris):612575 SPRED3

Monarch:612575 SPRED3

NCBI Gene:612575 SPRED3

Reference Transcript

RefSeq:XM_005616622.2 SPRED3

Other Identifiers

612575

CfaAffx.9846.1.S1_at

GO:0007275

GO:0009966

GO:0016020

GO:0023052

GO:0048856

Participates

as a component of

SPRED3 dimer [plasma membrane] (Canis familiaris)

Inferred From

SPRED3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005616679.1

OpenTargets

ENSG00000188766

Ensembl

ENSCAFG00845005619, ENSCAFT00845009970, ENSCAFP00845007780

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