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POLD,POLE [nucleoplasm]
Stable Identifier
R-CFA-5651800
Type
Set [CandidateSet]
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Canis familiaris)
Base Excision Repair (Canis familiaris)
Resolution of Abasic Sites (AP sites) (Canis familiaris)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Canis familiaris)
PCNA-Dependent Long Patch Base Excision Repair (Canis familiaris)
LIG1 binds APEX1 and PCNA at SSB (Canis familiaris)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Canis familiaris)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
LIG1 bound to APEX1 and PCNA ligates SSB (Canis familiaris)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Canis familiaris)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Canis familiaris)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE-mediated DNA strand displacement synthesis (Canis familiaris)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
DNA Damage Bypass (Canis familiaris)
Recognition of DNA damage by PCNA-containing replication complex (Canis familiaris)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Canis familiaris)
Termination of translesion DNA synthesis (Canis familiaris)
POLD,POLE binds deISGylated PCNA after TLS (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
DNA Double-Strand Break Repair (Canis familiaris)
Homology Directed Repair (Canis familiaris)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Canis familiaris)
HDR through Homologous Recombination (HRR) (Canis familiaris)
D-loop extension by DNA polymerases (Canis familiaris)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Nucleotide Excision Repair (Canis familiaris)
Global Genome Nucleotide Excision Repair (GG-NER) (Canis familiaris)
Dual Incision in GG-NER (Canis familiaris)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE,POLK [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Gap-filling DNA repair synthesis and ligation in GG-NER (Canis familiaris)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Canis familiaris)
Dual incision in TC-NER (Canis familiaris)
3' incision by ERCC5 (XPG) in TC-NER (Canis familiaris)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Canis familiaris)
POLD,POLE,POLK [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Gap-filling DNA repair synthesis and ligation in TC-NER (Canis familiaris)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
POLD,POLE [nucleoplasm] (Canis familiaris)
Participants
members
DNA Polymerase delta tetramer [nucleoplasm]
(Canis familiaris)
candidates
DNA polymerase epsilon [nucleoplasm]
(Canis familiaris)
Participates
as an input of
POLD,POLE binds deISGylated PCNA after TLS (Canis familiaris)
as a component of
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Canis familiaris)
as an output of
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Canis familiaris)
as a member of
POLD,POLE,POLK [nucleoplasm] (Canis familiaris)
Inferred From
POLD,POLE [nucleoplasm]
(Homo sapiens)
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