Reactome | CNGA4 [Golgi membrane]

CNGA4 [Golgi membrane]

Stable Identifier

R-CFA-5624055

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

Golgi membrane

Synonyms

CNGA4, A0A8I3N510

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Canis familiaris)

- Cilium Assembly (Canis familiaris)
  - Cargo trafficking to the periciliary membrane (Canis familiaris)
    - VxPx cargo-targeting to cilium (Canis familiaris)
      - ARF4:GTP binds VxPx-motifs of membrane proteins (Canis familiaris)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
      - ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
      - ASAP1 stimulates GTPase activity of ARF4 (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
      - Cargo-carrying vesicles bud from the TGN (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
      - RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Canis familiaris)
        
        CNG tetramer [Golgi membrane] (Canis familiaris)
        
        CNGA4 [Golgi membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N510

Gene Names

CNGA4

Reference Genes

ENSEMBL:ENSCAFG00845007124.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845007124.1 CNGA4

Other Identifiers

476830

CfaAffx.10560.1.S1_at

GO:0005215

GO:0005216

GO:0005249

GO:0006811

GO:0006813

GO:0007608

GO:0016020

GO:0034220

GO:0050877

GO:0050896

GO:0055085

GO:0071805

Participates

as a component of

CNG tetramer [Golgi membrane] (Canis familiaris)

Other forms of this molecule

CNGA4 [ciliary membrane]

CNGA4 [Golgi-associated vesicle membrane]

Inferred From

CNGA4 [Golgi membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000132259

Ensembl

ENSCAFP00845009881, ENSCAFG00845007124, ENSCAFT00845012663

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