Reactome | MRPS18A [mitochondrial inner membrane]

MRPS18A [mitochondrial inner membrane]

Stable Identifier

R-CFA-5368200

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial inner membrane

Synonyms

MRPS18A, A0A8I3N5L6

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Translation (Canis familiaris)
  - Mitochondrial translation (Canis familiaris)
    - Mitochondrial translation elongation (Canis familiaris)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
    - Mitochondrial translation termination (Canis familiaris)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
      - MRRF binds 55S ribosome:mRNA:tRNA (Canis familiaris)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A [mitochondrial inner membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N5L6

Gene Names

MRPS18A

Reference Genes

BioGPS Gene:474917 MRPS18A

ENSEMBL:ENSCAFG00845010419.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845010419.1 MRPS18A

Monarch:474917 MRPS18A

NCBI Gene:474917 MRPS18A

Reference Transcript

RefSeq:XM_532152.5 MRPS18A

Other Identifiers

474917

Cfa.4495.1.A1_at

CfaAffx.3815.1.S1_at

CfaAffx.3815.1.S1_s_at

GO:0003735

GO:0005198

GO:0005739

GO:0005762

GO:0005763

GO:0005840

GO:0006412

GO:0043226

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)

Inferred From

MRPS18A [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

XP_532152.2

OpenTargets

ENSG00000096080

Ensembl

ENSCAFT00845018342, ENSCAFG00845010419, ENSCAFP00845014317

Cite Us!