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CYCS [cytosol]
Stable Identifier
R-CFA-53259
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
P00011
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Canis familiaris)
Apoptosis (Canis familiaris)
Intrinsic Pathway for Apoptosis (Canis familiaris)
Apoptotic factor-mediated response (Canis familiaris)
Cytochrome c-mediated apoptotic response (Canis familiaris)
Activation of caspases through apoptosome-mediated cleavage (Canis familiaris)
Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
Apoptosome [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Cleavage of Procaspase-7 by the apoptosome (Canis familiaris)
Apoptosome [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Formation of apoptosome (Canis familiaris)
CYCS binds to APAF1 (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
CYCS:APAF1 binds procaspase-9 (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Cleavage of Procaspase‑9 to caspase‑9 (Canis familiaris)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Apoptosome [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Procaspase 9 forms dimer (Canis familiaris)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Regulation of the apoptosome activity (Canis familiaris)
APAF1:CYCS binds APIP (Canis familiaris)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
APAF1:CYCS:ATP:APIP [cytosol] (Canis familiaris)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
CASP9 is phosphorylated at T412 (Canis familiaris)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Canis familiaris)
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
XIAP binds CASP9 (Canis familiaris)
Apoptosome [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
XIAP:apoptosome [cytosol] (Canis familiaris)
Apoptosome [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Release of apoptotic factors from the mitochondria (Canis familiaris)
Release of Cytochrome c from mitochondria (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
Regulated Necrosis (Canis familiaris)
Pyroptosis (Canis familiaris)
Release of Cytochrome c from mitochondria (Canis familiaris)
CYCS [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:P00011
Reference Genes
ENSEMBL:ENSCAFG00030004991
UCSC:P00011
Other Identifiers
475258
Cfa.379.1.S1_at
CfaAffx.5204.1.S1_s_at
GO:0005634
GO:0005739
GO:0005758
GO:0005829
GO:0043226
GO:0043293
Participates
as an input of
CYCS binds to APAF1 (Canis familiaris)
as an output of
Release of Cytochrome c from mitochondria (Canis familiaris)
as a component of
APAF1:ATP:CYCS [cytosol] (Canis familiaris)
APAF1:CYCS [cytosol] (Canis familiaris)
Other forms of this molecule
AcK-CYCS [mitochondrial intermembrane space]
apo-CYCS [mitochondrial inner membrane]
Cytochrome c (reduced) [mitochondrial inner membrane]
Cytochrome c (oxidised) [mitochondrial inner membrane]
CYCS [mitochondrial intermembrane space]
Inferred From
CYCS [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSCAFT00845018890
,
ENSCAFP00845014758
VGNC
50288
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