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SLC38A9 [lysosomal membrane]
Stable Identifier
R-CFA-5215938
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
lysosomal membrane
Synonyms
SLC38A9, A0A8I3PYA9
Locations in the PathwayBrowser
Expand all
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Active MTORC1 binds the ULK1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1 dissociates from ULK complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Rheb in the MTORC1 complex hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to starvation (Canis familiaris)
Amino acids regulate mTORC1 (Canis familiaris)
RRAGA,B exchanges GDP for GTP (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Canis familiaris)
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
PTEN Regulation (Canis familiaris)
Regulation of PTEN gene transcription (Canis familiaris)
MAF1 translocates to the nucleus (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylates MAF1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
MTOR signalling (Canis familiaris)
AKT1S1 (PRAS40) binds mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Energy dependent regulation of mTOR by LKB1-AMPK (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Formation of active mTORC1 complex (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 binds Ragulator:Rag dimers (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylates AKT1S1 (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1-mediated signalling (Canis familiaris)
Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Canis familiaris)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Canis familiaris)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Canis familiaris)
Active mTORC1 complex [lysosomal membrane] (Canis familiaris)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
SLC38A9 [lysosomal membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PYA9
Gene Names
SLC38A9
Reference Genes
BioGPS Gene:487210 SLC38A9
ENSEMBL:ENSCAFG00845027599.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845027599.1 SLC38A9
Monarch:487210 SLC38A9
NCBI Gene:487210 SLC38A9
Reference Transcript
RefSeq:XM_014108392.1 SLC38A9
RefSeq:XM_014108398.1 SLC38A9
RefSeq:XM_014108396.1 SLC38A9
RefSeq:XM_014108400.1 SLC38A9
Other Identifiers
487210
CfaAffx.11195.1.S1_at
GO:0003333
GO:0005085
GO:0005215
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0006867
GO:0006868
GO:0008289
GO:0015171
GO:0015182
GO:0015186
GO:0015190
GO:0015485
GO:0023052
GO:0031410
GO:0032008
GO:0032935
GO:0043226
GO:0055085
GO:0061459
GO:0071230
GO:0071986
GO:0098772
GO:0140299
GO:1903826
GO:1904263
GO:1990877
Participates
as a component of
SLC38A9:L-Arg [lysosomal membrane] (Canis familiaris)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Canis familiaris)
as an input of
SLC38A9 binds Ragulator:Rag dimers (Canis familiaris)
Inferred From
SLC38A9 [lysosomal membrane]
(Homo sapiens)
Cross References
RefSeq
XP_013963873.1
,
XP_013963875.1
,
XP_013963871.1
,
XP_013963867.1
OpenTargets
ENSG00000177058
Ensembl
ENSCAFT00845048716
,
ENSCAFG00845027599
,
ENSCAFP00845038219
© 2024
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