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phospho-CYLD [cytosol]
Stable Identifier
R-CFA-5212667
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-S418-CYLD, A0A8I3MSL4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
TNF signaling (Canis familiaris)
Regulation of TNFR1 signaling (Canis familiaris)
CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)
phospho-CYLD [cytosol] (Canis familiaris)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Canis familiaris)
phospho-CYLD [cytosol] (Canis familiaris)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Canis familiaris)
phospho-CYLD [cytosol] (Canis familiaris)
K63polyUb-RIPK1 is deubiquitinated (Canis familiaris)
phospho-CYLD [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MSL4
Gene Names
CYLD
Reference Genes
BioGPS Gene:611649 CYLD
ENSEMBL:ENSCAFG00845003806.1
KEGG:cfa:611649 CYLD
Monarch:611649 CYLD
NCBI Gene:611649 CYLD
UCSC:A0A8I3MSL4 CYLD
Reference Transcript
RefSeq:XM_005617567.2 CYLD
RefSeq:XM_849343.4 CYLD
Other Identifiers
611649
CfaAffx.15385.1.S1_s_at
GO:0002376
GO:0003824
GO:0004843
GO:0005737
GO:0005813
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0005874
GO:0005881
GO:0005886
GO:0007346
GO:0008270
GO:0009898
GO:0010803
GO:0012501
GO:0016055
GO:0016579
GO:0016787
GO:0019901
GO:0030496
GO:0036064
GO:0042995
GO:0043226
GO:0043369
GO:0045087
GO:0045577
GO:0045582
GO:0046329
GO:0048471
GO:0048872
GO:0050727
GO:0050728
GO:0050862
GO:0060544
GO:0061578
GO:0065003
GO:0070064
GO:0070266
GO:0070507
GO:0070536
GO:0090090
GO:0097542
GO:0098542
GO:0140096
GO:1901026
GO:1901223
GO:1902017
GO:1903753
GO:1903829
GO:1990108
GO:1990380
GO:2000493
GO:2001238
GO:2001242
Participates
as an output of
CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)
This entity regulates
Negatively
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex
(Canis familiaris)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex
(Canis familiaris)
K63polyUb-RIPK1 is deubiquitinated
(Canis familiaris)
Other forms of this molecule
CYLD [cytosol]
CYLD [cytosol]
Inferred From
p-S418-CYLD [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 418 (in Homo sapiens)
Coordinate
418
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_854436.1
,
XP_005617624.1
ENSEMBL
ENSCAFP00845005437
,
ENSCAFT00845006826
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