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K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
Stable Identifier
R-CFA-5205659
Type
Complex
Species
Canis familiaris
Compartment
mitochondrial outer membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Selective autophagy (Canis familiaris)
Mitophagy (Canis familiaris)
PINK1-PRKN Mediated Mitophagy (Canis familiaris)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Canis familiaris)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Canis familiaris)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Canis familiaris)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Canis familiaris)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Canis familiaris)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Canis familiaris)
p62 binds ubiquitinated mitochondrial substrates (Canis familiaris)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Canis familiaris)
p62 links damaged mitochondria to LC3 (Canis familiaris)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Canis familiaris)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Canis familiaris)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
K48polyUb-MOM proteins [mitochondrial outer membrane]
(Canis familiaris)
SQSTM1 [cytosol]
(Canis familiaris)
Participates
as an input of
p62 links damaged mitochondria to LC3 (Canis familiaris)
as a component of
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Canis familiaris)
as an output of
p62 binds ubiquitinated mitochondrial substrates (Canis familiaris)
Inferred From
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
(Homo sapiens)
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