Reactome | MBD3 [nucleoplasm]

MBD3 [nucleoplasm]

Stable Identifier

R-CFA-4657010

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

MBD3, A0A8I3P214

Locations in the PathwayBrowser

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Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase I Transcription (Canis familiaris)
  - RNA Polymerase I Promoter Clearance (Canis familiaris)
    - RNA Polymerase I Transcription Initiation (Canis familiaris)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Canis familiaris)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Canis familiaris)
        
        NuRD complex [nucleoplasm] (Canis familiaris)
        
        MBD3 [nucleoplasm] (Canis familiaris)
- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - Regulation of TP53 Activity (Canis familiaris)
        
        Regulation of TP53 Activity through Acetylation (Canis familiaris)
        
        MTA2-NuRD complex deacetylates TP53 (Canis familiaris)
        
        MTA2-NuRD complex [nucleoplasm] (Canis familiaris)
        
        MBD3 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Intracellular signaling by second messengers (Canis familiaris)
  - PIP3 activates AKT signaling (Canis familiaris)
    - PTEN Regulation (Canis familiaris)
      - Regulation of PTEN gene transcription (Canis familiaris)
        
        SALL4 recruits NuRD to PTEN gene (Canis familiaris)
        
        NuRD complex [nucleoplasm] (Canis familiaris)
        
        MBD3 [nucleoplasm] (Canis familiaris)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Canis familiaris)
        
        SALL4:NuRD [nucleoplasm] (Canis familiaris)
        
        NuRD complex [nucleoplasm] (Canis familiaris)
        
        MBD3 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P214

Gene Names

MBD3

Reference Genes

ENSEMBL:ENSCAFG00845014226.1

UCSC:A0A8I3P214 MBD3

Other Identifiers

485080

CfaAffx.29817.1.S1_s_at

GO:0000122

GO:0000785

GO:0000792

GO:0001701

GO:0003677

GO:0005634

GO:0005654

GO:0005737

GO:0006325

GO:0006338

GO:0006346

GO:0006355

GO:0008327

GO:0009888

GO:0016581

GO:0032991

GO:0043226

GO:0043227

GO:0043229

GO:0048856

Participates

as a component of

Inferred From

MBD3 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845025489, ENSCAFP00845020070, ENSCAFG00845014226