Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
JAK1 [cytosol]
Stable Identifier
R-CFA-451898
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
JAK1, A0A8I3RS40
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
ISG15 antiviral mechanism (Canis familiaris)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Canis familiaris)
ISG15 targets [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
ISGylated host proteins [cytosol] (Canis familiaris)
ISG15 targets [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interferon alpha/beta signaling (Canis familiaris)
Activation of JAK kinases (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFN alpha/beta binds to IFNAR2 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Recruitment of IFNAR1 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Regulation of IFNA/IFNB signaling (Canis familiaris)
Dephosphorylation of JAK1 by SHP1 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interferon gamma signaling (Canis familiaris)
IFNG dimer binds IFNGR (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Phosphorylation of JAK2 (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR complex with p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Regulation of IFNG signaling (Canis familiaris)
SOCS-1 and SOCS-3 binds to p-JAK2 (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR complex with p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR complex with p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Transphosphorylation of JAK1 (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR complex with p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] (Canis familiaris)
IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR complex with p-JAK2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Signaling by CSF3 (G-CSF) (Canis familiaris)
CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Canis familiaris)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 (Canis familiaris)
CSF3 dimer:2xCSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-10 signaling (Canis familiaris)
IL10 dimer binds IL10RA:JAK1 (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-12 family signaling (Canis familiaris)
Interleukin-12 signaling (Canis familiaris)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
p-Y800-IL12RB2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
p-Y800-IL12RB2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2:2xSTAT4 [plasma membrane] (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
p-Y800-IL12RB2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
p-Y693-STAT4 dissociates after IL12:IL12R interaction (Canis familiaris)
2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
p-Y800-IL12RB2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12RB1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-27 signaling (Canis familiaris)
Interleukin-27 binds Interleukin-27 receptor (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-27 dissociates from Interleukin-27 receptor (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Canis familiaris)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-35 Signalling (Canis familiaris)
IL35 binds IL-12RB2:IL6ST receptor (Canis familiaris)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL35 binds IL27RA:IL12RB2 receptor (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL35 binds IL6ST:IL6ST receptor (Canis familiaris)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Canis familiaris)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin-15 signaling (Canis familiaris)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Canis familiaris)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-2 signaling (Canis familiaris)
IL2RB binds JAK1 (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Canis familiaris)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Canis familiaris)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Canis familiaris)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-21 signaling (Canis familiaris)
IL21 binds IL21R:JAK1 (Canis familiaris)
IL21:IL21R:JAK1 [plasma membrane] (Canis familiaris)
IL21R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL21R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL21 receptor JAK phosphorylation (Canis familiaris)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL21:IL21R:JAK1 [plasma membrane] (Canis familiaris)
IL21R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-9 signaling (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Canis familiaris)
IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9R binds JAK1 (Canis familiaris)
IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Canis familiaris)
IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Canis familiaris)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-20 family signaling (Canis familiaris)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL19 binds IL20RA:JAK1:IL20RB (Canis familiaris)
IL19:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
IL19:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20 binds IL20RA:JAK1:IL20RB (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20 binds to IL22RA1:JAK1:IL20RB (Canis familiaris)
IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:STAT3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:p-STAT3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:STAT3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20RA binds IL20RB (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22 binds IL22RA1:JAK1 receptor complex (Canis familiaris)
IL22:IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL22:IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL22:IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL22:IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL22RA1 binds JAK1 (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL24 binds IL20RA:JAK1:IL20RB (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL24:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL24 binds to IL22RA1:JAK1:IL20RB (Canis familiaris)
IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL24:IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
IL24:IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL26 binds IL20RA:JAK1 (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL26:IL20RA:JAK1 [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL26:IL20RA:JAK1 [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1 [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1 [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 binds IFNLR1 (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 binds IL20RA (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Canis familiaris)
IL24:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:p-STAT3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 [plasma membrane] (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1:IL20RB [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-4 and Interleukin-13 signaling (Canis familiaris)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 binds IL4R in IL13-bound IL13R type II (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 binds IL4R in IL4-bound IL4R1 (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
STAT1,STAT3,STAT6 bind IL13:IL13R type II (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
STAT1,STAT3,STAT6 phosphorylation (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
p-Y-STATs dissociate (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-6 family signaling (Canis familiaris)
IL-6-type cytokine receptor ligand interactions (Canis familiaris)
CTF1 binds LIFR:JAKs (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL31:IL31RA:JAK1 binds OSMR:JAK1 (Canis familiaris)
IL31:IL31RA:JAK1 [plasma membrane] (Canis familiaris)
IL31RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL31:IL31RA:JAK1:OSMR:JAK1 [plasma membrane] (Canis familiaris)
IL31:IL31RA:JAK1 [plasma membrane] (Canis familiaris)
IL31RA:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSMR:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSMR:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs bind LIFR (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs bind OSMR (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIF binds LIFR (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIFR:JAKs bind gp130:JAKs:CNTFR (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSM binds LIFR:JAKs,OSMR:JAKs (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSM,LIF,CTF1 receptor complex binds gp130 (Canis familiaris)
LIF,OSM receptor complex:gp130 [plasma membrane] (Canis familiaris)
LIF,OSM,CTF1 receptor complex [plasma membrane] (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIF,OSM,CTF1 receptor complex [plasma membrane] (Canis familiaris)
CTF1:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
LIF:LIFR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
OSM:OSMR,LIFR [plasma membrane] (Canis familiaris)
LIFR:JAKs,OSMR:JAKs [plasma membrane] (Canis familiaris)
JAKs:LIFR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAKs:OSMR [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
gp130:JAKs bind CNTFR (Canis familiaris)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-6 signaling (Canis familiaris)
Assembly of hexameric IL-6 receptor (Canis familiaris)
IL6 receptor hexamer:JAKs [plasma membrane] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK activation (Canis familiaris)
IL6 receptor hexamer:JAKs [plasma membrane] (Canis familiaris)
IL6 receptor trimer:JAKs [plasma membrane] (Canis familiaris)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Canis familiaris)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Interleukin-7 signaling (Canis familiaris)
IL7 binds IL7R:JAK1 (Canis familiaris)
IL7:IL7R:JAK1 [plasma membrane] (Canis familiaris)
IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Canis familiaris)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Canis familiaris)
IL7:IL7R:JAK1 [plasma membrane] (Canis familiaris)
IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:IL7R:JAK1 [plasma membrane] (Canis familiaris)
IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Canis familiaris)
IL7:p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
Other interleukin signaling (Canis familiaris)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
JAK1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3RS40
Gene Names
JAK1
Reference Genes
ENSEMBL:ENSCAFG00845004547.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845004547.1 JAK1
Other Identifiers
442952
Cfa.10348.1.S1_at
Cfa.15782.2.S1_s_at
Cfa.5836.1.A1_at
CfaAffx.28443.1.S1_s_at
CfaAffx.28446.1.S1_at
CfaAffx.28447.1.S1_s_at
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005524
GO:0005634
GO:0005737
GO:0005856
GO:0005886
GO:0006468
GO:0007155
GO:0007259
GO:0009898
GO:0016020
GO:0016740
GO:0019903
GO:0023052
GO:0031234
GO:0031625
GO:0034112
GO:0035556
GO:0035723
GO:0035771
GO:0036211
GO:0038110
GO:0038113
GO:0038154
GO:0043226
GO:0046677
GO:0048856
GO:0060333
GO:0060337
GO:0070102
GO:0098542
GO:0140096
GO:0150105
GO:1900182
GO:1903672
Participates
as a component of
IL12RB1:JAK1 [plasma membrane] (Canis familiaris)
IL27RA:JAK1 [plasma membrane] (Canis familiaris)
IL13:IL13RA:TYK2:IL4R:JAK2:JAK1 [plasma membrane] (Canis familiaris)
IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Canis familiaris)
CSF3R:LYN:JAK1 [plasma membrane] (Canis familiaris)
IL22RA1:JAK1 [plasma membrane] (Canis familiaris)
IL10RA:JAK1 [plasma membrane] (Canis familiaris)
IL20RA:JAK1 [plasma membrane] (Canis familiaris)
IFNLR1:JAK1 [plasma membrane] (Canis familiaris)
OSMR:JAK1 [plasma membrane] (Canis familiaris)
IL31RA:JAK1 [plasma membrane] (Canis familiaris)
IL21R:JAK1 [plasma membrane] (Canis familiaris)
IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y449-IL7R:JAK1 [plasma membrane] (Canis familiaris)
p-Y407-IL9R:JAK1 [plasma membrane] (Canis familiaris)
IL9R:JAK1 [plasma membrane] (Canis familiaris)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNGR1:JAK1 [plasma membrane] (Canis familiaris)
IL2RB:JAK1 [plasma membrane] (Canis familiaris)
as an input of
JAK1 binds IL4R in IL13-bound IL13R type II (Canis familiaris)
IL22RA1 binds JAK1 (Canis familiaris)
JAK1 binds IL20RA (Canis familiaris)
JAK1 binds IFNLR1 (Canis familiaris)
IL9R binds JAK1 (Canis familiaris)
JAK1 binds IL4R in IL4-bound IL4R1 (Canis familiaris)
IL2RB binds JAK1 (Canis familiaris)
as a member of
ISG15 targets [cytosol] (Canis familiaris)
JAK1, JAK2, (TYK2) [cytosol] (Canis familiaris)
Other forms of this molecule
phospho-JAK1 [cytosol]
JAK1 [endosome]
phospho-JAK1 [cytosol]
phospho-JAK1 [cytosol]
phospho-JAK1 [cytosol]
Inferred From
JAK1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000162434
Ensembl
ENSCAFT00845008187
,
ENSCAFG00845004547
,
ENSCAFP00845006435
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text