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NFKB1 [cytosol]
Stable Identifier
R-CFA-451607
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
NFKB1(1-968), Q6F3J0
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MAP3K8 is phosphorylated (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:Q6F3J0
Gene Names
NFKB1
Reference Genes
BioGPS Gene:442859 NFKB1
ENSEMBL:ENSCAFG00000010730
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000010730.5 NFKB1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00030020386.1 NFKB1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00040022966.1 NFKB1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00805029346 NFKB1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025570.1 NFKB1
KEGG Gene (Canis lupus familiaris):442859 NFKB1
Monarch:442859 NFKB1
NCBI Gene:442859 NFKB1
Reference Transcript
RefSeq:NM_001003344.1 NFKB1
Other Identifiers
442859
Cfa.10766.1.S1_at
CfaAffx.16794.1.S1_s_at
GO:0003677
GO:0003700
GO:0005515
GO:0005737
GO:0006351
GO:0006355
GO:0007165
GO:0023052
GO:0140110
Participates
as an input of
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Canis familiaris)
as a component of
NFKB1:p-S400-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Canis familiaris)
NFKB1:MAP3K8:TNIP2 [cytosol] (Canis familiaris)
Other forms of this molecule
NFKB1 [specific granule lumen]
NFKB1 [extracellular region]
NFKB1 [secretory granule lumen]
NFKB1 [cytosol]
NFKB1 [nucleoplasm]
phospho-NFKB1 [cytosol]
phospho-NFKB1 [cytosol]
Inferred From
NFKB1(1-968) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001003344.1
OpenTargets
ENSG00000109320
Ensembl
ENSCAFG00845025570
,
ENSCAFT00845045189
,
ENSCAFP00845035432
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