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p-Pellino-1,2,(3) [cytosol]
Stable Identifier
R-CFA-450819
Type
Set [CandidateSet]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
K63polyUb-IRAK1 dissociates (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates IRAK1 (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Canis familiaris)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Canis familiaris)
IRAK4: p-Pellino-1,2,3 [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Canis familiaris)
IRAK1:Pellino:E2 complexes [cytosol] (Canis familiaris)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Canis familiaris)
IRAK4: p-Pellino-1,2,3 [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Canis familiaris)
IRAK4: p-Pellino-1,2,3 [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
Participants
members
phospho-PELI1 [cytosol]
(Canis familiaris)
phospho-PELI2 [cytosol]
(Canis familiaris)
candidates
phospho-PELI3 [cytosol]
(Canis familiaris)
Participates
as an output of
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
K63polyUb-IRAK1 dissociates (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
as an input of
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Canis familiaris)
Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)
as a component of
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Canis familiaris)
IRAK4: p-Pellino-1,2,3 [cytosol] (Canis familiaris)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Canis familiaris)
Inferred From
p-Pellino-1,2,(3) [cytosol]
(Homo sapiens)
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