Reactome | IL12A:IL12B [extracellular region]

IL12A:IL12B [extracellular region]

Stable Identifier

R-CFA-447102

Type

Complex

Species

Canis familiaris

Compartment

extracellular region

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

IL12A [extracellular region] (Canis familiaris)
IL12B [extracellular region] (Canis familiaris)

Participates

as an input of

Interleukin-12 binds Interleukin-12 receptor (Canis familiaris)

as an output of

Interleukin-12 dissociates from Interleukin-12 receptor (Canis familiaris)
IL12A:IL12B translocates from late endosome lumen to extracellular region (Canis familiaris)

as a component of

IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12A:IL12B:IL12RB1:p-Y-TYK2:IL12RB2:p-JAK2 [plasma membrane] (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)

Inferred From

IL12A:IL12B [extracellular region] (Homo sapiens)

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