Reactome | RLN3 [extracellular region]

RLN3 [extracellular region]

Stable Identifier

R-CFA-444849

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

RLN3(26-52), A0A8I3PPP9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Relaxin receptors (Canis familiaris)
        
        Relaxin 3 receptor 1 binds relaxin 3 (Canis familiaris)
        
        RXFP3:Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Relaxin receptor 1 binds relaxin 2 and 3 (Canis familiaris)
        
        RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Canis familiaris)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Canis familiaris)
        
        Relaxin-3 [extracellular region] (Canis familiaris)
        
        RLN3 [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PPP9

Gene Names

RLN3

Reference Genes

ENSEMBL:ENSCAFG00845025377.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025377.1 RLN3

Other Identifiers

119864730

CfaAffx.25261.1.S1_at

GO:0005179

GO:0005576

GO:0007165

GO:0023052

GO:0048018

GO:0098772

Participates

as a component of

Relaxin-3 [extracellular region] (Canis familiaris)

Other forms of this molecule

RLN3 [extracellular region]

Inferred From

RLN3(26-52) [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000171136

Ensembl

ENSCAFG00845025377, ENSCAFP00845035084, ENSCAFT00845044771