Reactome | TAS1R1 [plasma membrane]

TAS1R1 [plasma membrane]

Stable Identifier

R-CFA-444666

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

TAS1R1, A0A8I3Q7L4

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Canis familiaris)
      - T1R1/T1R3 dimer is the umami taste receptor (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Canis familiaris)
        
        TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)
        
        TAS1R1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q7L4

Gene Names

TAS1R1

Reference Genes

BioGPS Gene:489633 TAS1R1

ENSEMBL:ENSCAFG00845025663.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025663.1 TAS1R1

KEGG Gene (Canis lupus familiaris):489633 TAS1R1

Monarch:489633 TAS1R1

NCBI Gene:489633 TAS1R1

Reference Transcript

RefSeq:XM_005620469.2 TAS1R1

Other Identifiers

489633

CfaAffx.29982.1.S1_at

CfaAffx.29982.1.S1_s_at

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0023052

GO:0050877

GO:0050912

GO:0050917

GO:0060089

Participates

as a component of

TAS1R1:TAS1R3 [plasma membrane] (Canis familiaris)

Inferred From

TAS1R1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005620526.2

OpenTargets

ENSG00000173662

Ensembl

ENSCAFP00845035558, ENSCAFG00845025663, ENSCAFT00845045336