Reactome | GRM6 [plasma membrane]

GRM6 [plasma membrane]

Stable Identifier

R-CFA-420574

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GRM6, F1P8E3

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Canis familiaris)
      - Metabotropic glutamate receptors bind glutamate (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)
        
        GRM1-8:L-Glu [plasma membrane] (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM6 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1P8E3

Gene Names

GRM6

Reference Genes

ENSEMBL:ENSCAFG00000000332

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000000332 GRM6

Other Identifiers

481452

Cfa.6589.1.A1_s_at

GO:0000139

GO:0001642

GO:0003674

GO:0004930

GO:0005575

GO:0005622

GO:0005737

GO:0005789

GO:0005794

GO:0005886

GO:0005887

GO:0006810

GO:0007165

GO:0007186

GO:0007196

GO:0007216

GO:0007267

GO:0007626

GO:0008066

GO:0008150

GO:0016020

GO:0016021

GO:0035841

GO:0042803

GO:0043226

GO:0048856

GO:0050877

GO:0050908

GO:0050953

GO:0051966

GO:0060041

GO:0090280

Participant Of

hasMember

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane]

Inferred From

GRM6 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000113262

Ensembl

ENSCAFG00000000332, ENSCAFP00000000460, ENSCAFT00000000509

VGNC

41513

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