Reactome | S1PR5 [plasma membrane]

S1PR5 [plasma membrane]

Stable Identifier

R-CFA-419420

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

S1PR5, A0A8I3Q0H0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Lysosphingolipid and LPA receptors (Canis familiaris)
        
        S1PR2-5 bind S1P (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR5 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q0H0

Gene Names

S1PR5

Reference Genes

BioGPS Gene:610828 S1PR5

ENSEMBL:ENSCAFG00845026691.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845026691.1 S1PR5

KEGG Gene (Canis lupus familiaris):610828 S1PR5

Monarch:610828 S1PR5

NCBI Gene:610828 S1PR5

Reference Transcript

Other Identifiers

610828

CfaAffx.27195.1.S1_at

GO:0004930

GO:0007186

GO:0016020

GO:0023052

GO:0038036

GO:0060089

Participates

as a member of

S1PR2-5 [plasma membrane] (Canis familiaris)

Inferred From

S1PR5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005632952.1, XP_005632953.1

OpenTargets

ENSG00000180739

Ensembl

ENSCAFP00845036905, ENSCAFG00845026691, ENSCAFT00845047030