Reactome | PDE5A [cytosol]

PDE5A [cytosol]

Stable Identifier

R-CFA-418508

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

A0A8I3Q3W1

Locations in the PathwayBrowser

Expand all

Hemostasis (Canis familiaris)

- Platelet homeostasis (Canis familiaris)
  - Nitric oxide stimulates guanylate cyclase (Canis familiaris)
    - cGMP effects (Canis familiaris)
      - cGMP is degraded by PDEs (Canis familiaris)
        
        cGMP phosphodiesterases [cytosol] (Canis familiaris)
        
        Phosphodiesterases, cyclic GMP-selective [cytosol] (Canis familiaris)
        
        Homologues of PDE5A [cytosol] (Canis familiaris)
        
        PDE5A [cytosol] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
  - Signaling by Rho GTPases (Canis familiaris)
    - RHO GTPase cycle (Canis familiaris)
      - RHOBTB GTPase Cycle (Canis familiaris)
        
        RHOBTB1 GTPase cycle (Canis familiaris)
        
        RHOBTB1 binds interacting proteins at the endosome membrane (Canis familiaris)
        
        RHOBTB1 interacting proteins [cytosol] (Canis familiaris)
        
        Homologues of PDE5A [cytosol] (Canis familiaris)
        
        PDE5A [cytosol] (Canis familiaris)
        
        RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Canis familiaris)
        
        RHOBTB1 interacting proteins [cytosol] (Canis familiaris)
        
        Homologues of PDE5A [cytosol] (Canis familiaris)
        
        PDE5A [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q3W1

Reference Genes

ENSEMBL:ENSCAFG00845030199.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845030199.1

Other Identifiers

403825

Cfa.1752.1.S1_at

Cfa.1752.1.S2_at

Cfa.1752.2.S1_s_at

GO:0003824

GO:0004114

GO:0005515

GO:0007165

GO:0008081

GO:0016787

GO:0023052

GO:0046872

Participates

as a member of

Homologues of PDE5A [cytosol] (Canis familiaris)

Inferred From

PDE5A [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSCAFT00845053663, ENSCAFG00845030199, ENSCAFP00845042165

© 2024 Reactome

Cite Us!