Reactome | SFTPD [extracellular region]

SFTPD [extracellular region]

Stable Identifier

R-CFA-391099

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

SFTPD, A0A8I3NUR4

Locations in the PathwayBrowser

Expand all

Cell-Cell communication (Canis familiaris)

- Signal regulatory protein family interactions (Canis familiaris)
  - SIRPA binds SFTPA oligomer, SFTPD oligomer (Canis familiaris)
    - SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
      - SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
    - SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] (Canis familiaris)
      - SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)

Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Canis familiaris)
    - OSCAR binds collagen and SP-D (Canis familiaris)
      - Collagen types I,II,III/SP-D [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
      - OSCAR:Collagen I,II,III/SP-D [extracellular region] (Canis familiaris)
        
        Collagen types I,II,III/SP-D [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
- Innate Immune System (Canis familiaris)
  - Toll-like Receptor Cascades (Canis familiaris)
    - Regulation of TLR by endogenous ligand (Canis familiaris)
      - SFTPA/SFTPD binds TLR2:TLR1 (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
        
        SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
      - SFTPA/SFTPD binds TLR4:LY96 (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
        
        SP-A/SP-D:TLR4:MD2 [plasma membrane] (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)
    - Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
      - Transfer of LPS onto TLR4 (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPD trimer [extracellular region] (Canis familiaris)
        
        SFTPD [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NUR4

Gene Names

SFTPD

Reference Genes

BioGPS Gene:489066 SFTPD

ENSEMBL:ENSCAFG00845014766.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845014766.1 SFTPD

KEGG Gene (Canis lupus familiaris):489066 SFTPD

Monarch:489066 SFTPD

NCBI Gene:489066 SFTPD

Reference Transcript

RefSeq:XM_546184.4 SFTPD

Other Identifiers

489066

CfaAffx.24148.1.S1_s_at

GO:0005581

GO:0030246

Participates

as a component of

SFTPD trimer [extracellular region] (Canis familiaris)

Other forms of this molecule

SFTPD [endoplasmic reticulum membrane]

SFTPD [clathrin-coated endocytic vesicle]

Inferred From

SFTPD [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_546184.2

OpenTargets

ENSG00000133661

Ensembl

ENSCAFT00845026394, ENSCAFP00845020804, ENSCAFG00845014766