Reactome | SFTPA1 [extracellular region]

SFTPA1 [extracellular region]

Stable Identifier

R-CFA-391093

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

F1PYI4

Locations in the PathwayBrowser

Expand all

Cell-Cell communication (Canis familiaris)

- Signal regulatory protein family interactions (Canis familiaris)
  - SIRPA binds SFTPA oligomer, SFTPD oligomer (Canis familiaris)
    - SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
      - SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)
    - SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] (Canis familiaris)
      - SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)

Immune System (Canis familiaris)

- Innate Immune System (Canis familiaris)
  - Toll-like Receptor Cascades (Canis familiaris)
    - Regulation of TLR by endogenous ligand (Canis familiaris)
      - SFTPA/SFTPD binds TLR2:TLR1 (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)
        
        SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)
      - SFTPA/SFTPD binds TLR4:LY96 (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)
        
        SP-A/SP-D:TLR4:MD2 [plasma membrane] (Canis familiaris)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Canis familiaris)
        
        SFTPA oligomer [extracellular region] (Canis familiaris)
        
        SFTPA trimer [extracellular region] (Canis familiaris)
        
        SFTPA1 [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PYI4

Reference Genes

ENSEMBL:ENSCAFG00000015754

Participates

as a component of

SFTPA trimer [extracellular region] (Canis familiaris)

Other forms of this molecule

SFTPA1 [lamellar body]

SFTPA1 [endoplasmic reticulum membrane]

SFTPA1 [clathrin-coated endocytic vesicle]

Inferred From

SFTPA [extracellular region] (Homo sapiens)

SFTPA2 [extracellular region] (Homo sapiens)

SFTPA1 [extracellular region] (Homo sapiens)