Reactome | TNNI2 [cytosol]

TNNI2 [cytosol]

Stable Identifier

R-CFA-390538

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

TNNI2, A0A8I3NAA3

Locations in the PathwayBrowser

Expand all

Muscle contraction (Canis familiaris)

- Striated Muscle Contraction (Canis familiaris)
  - ATP Hydrolysis By Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
  - Calcium Binds Troponin-C (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
    - Inactive Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament [cytosol] (Canis familiaris)
        
        Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
  - Myosin Binds ATP (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
  - Release Of ADP From Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Calcium:Troponin Complex [cytosol] (Canis familiaris)
        
        Troponin I [cytosol] (Canis familiaris)
        
        TNNI2 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NAA3

Gene Names

TNNI2

Reference Genes

BioGPS Gene:475995 TNNI2

ENSEMBL:ENSCAFG00845010504.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845010504.1 TNNI2

Monarch:475995 TNNI2

NCBI Gene:475995 TNNI2

Reference Transcript

RefSeq:XM_845975.4 TNNI2

Other Identifiers

475995

Cfa.15780.1.S1_at

CfaAffx.15787.1.S1_s_at

GO:0005856

GO:0005861

GO:0043226

Participates

as a member of

Troponin I [cytosol] (Canis familiaris)

Inferred From

TNNI2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_851068.1

OpenTargets

ENSG00000130598

Ensembl

ENSCAFP00845014435, ENSCAFT00845018503, ENSCAFG00845010504