Reactome | PYY [extracellular region]

PYY [extracellular region]

Stable Identifier

R-CFA-388878

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

PYY(29-64), A0A8I3RXC1

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)
        
        Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Canis familiaris)
        
        NPY receptor ligands [extracellular region] (Canis familiaris)
        
        PYY [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3RXC1

Gene Names

PYY

Reference Genes

ENSEMBL:ENSCAFG00845009862.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009862.1 PYY

Reference Transcript

RefSeq:XM_843753.4 PYY

Other Identifiers

607156

GO:0001664

GO:0005179

GO:0005576

GO:0048018

GO:0098772

Participates

as a member of

NPY receptor ligands [extracellular region] (Canis familiaris)

Inferred From

PYY(29-64) [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_848846.1

OpenTargets

ENSG00000131096

Ensembl

ENSCAFT00845017370, ENSCAFG00845009862, ENSCAFP00845013528