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What is Reactome ?
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CENPK [cytosol]
Stable Identifier
R-CFA-375296
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
CENPK, A0A8I3NB51
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
Mitotic Spindle Checkpoint (Canis familiaris)
Amplification of signal from the kinetochores (Canis familiaris)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Canis familiaris)
MAD2 associates with the Mad1 kinetochore complex (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
MAD2 converted to an inhibitory state via interaction with Mad1 (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Mad1 binds kinetochore (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Release of activated MAD2 from kinetochores (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Separation of Sister Chromatids (Canis familiaris)
ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Separation of sister chromatids (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
EML4 recruits NUDC to mitotic spindle (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore capture of astral microtubules (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore assembly (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
CCAN network [cytosol] (Canis familiaris)
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
CENPK [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NB51
Gene Names
CENPK
Reference Genes
BioGPS Gene:609707 CENPK
ENSEMBL:ENSCAFG00845009602.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009602.1 CENPK
Monarch:609707 CENPK
NCBI Gene:609707 CENPK
Reference Transcript
RefSeq:XM_847023.3 CENPK
Other Identifiers
609707
CfaAffx.11953.1.S1_at
GO:0000775
GO:0000939
GO:0005634
GO:0005694
GO:0043226
GO:0051382
GO:0065003
Participates
as a component of
CENP-(H,I, K) complex [cytosol] (Canis familiaris)
Other forms of this molecule
CENPK [nucleoplasm]
Inferred From
CENPK [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_852116.1
OpenTargets
ENSG00000123219
Ensembl
ENSCAFG00845009602
,
ENSCAFT00845016937
,
ENSCAFP00845013184
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