Reactome | SSTR1 [plasma membrane]

SSTR1 [plasma membrane]

Stable Identifier

R-CFA-374741

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

SSTR1, Q49LX5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Somatostatin receptors bind somatostatin and cortistatin (Canis familiaris)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)
        
        Somatostatin receptors [plasma membrane] (Canis familiaris)
        
        SSTR1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:Q49LX5

Gene Names

SSTR1

Reference Genes

BioGPS Gene:403455 SSTR1

ENSEMBL:ENSCAFG00000013755

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000013755.5 SSTR1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00040000183.1 SSTR1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00805005771 SSTR1

KEGG Gene (Canis lupus familiaris):403455 SSTR1

Monarch:403455 SSTR1

NCBI Gene:403455 SSTR1

Reference Transcript

RefSeq:NM_001031816.1 SSTR1

Participates

as a member of

Somatostatin receptors [plasma membrane] (Canis familiaris)

Inferred From

SSTR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001026986.1

OpenTargets

ENSG00000139874

VGNC

46843